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Image Search Results
Journal: Frontiers in Endocrinology
Article Title: Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics
doi: 10.3389/fendo.2024.1438405
Figure Lengend Snippet: Impact of Resveratrol on Serum Biochemical Markers and TLR4, MyD88, NF-κB mRNA in Rat Ankle Synovial Tissue. (A) Impact of Resveratrol on Serum SUA in GA Rats; (B) Impact of Resveratrol on Serum SCr in GA Rats; (C) Impact of Resveratrol on Serum BUN in GA Rats; (D) Impact of Resveratrol on Serum MPO in GA Rats; (E) Impact of Resveratrol on Serum ROS in GA Rats; (F) Impact of Resveratrol on Serum IL-1β in GA Rats; (G) Impact of Resveratrol on Serum IL-6 in GA Rats; (H) Impact of Resveratrol on Serum IL-8 in GA Rats; (I) Impact of Resveratrol on Serum IL-12 in GA Rats; (J) Impact of Resveratrol on Serum IL-18 in GA Rats; (K) Impact of Resveratrol on Serum TNF-α in GA Rats; (L) Impact of Resveratrol on TLR4 mRNA in GA Rat Ankle Synovial Tissue; (M) Impact of Resveratrol on MyD88 mRNA in GA Rat Ankle Synovial Tissue; (N) Impact of Resveratrol on NF-κB mRNA in GA Rat Ankle Synovial Tissue. Compared to the blank control group, # p<0.05, ## p<0.01; Compared to the model group, *p<0.05, **p<0.01.
Article Snippet: Resveratrol (PubChem CID:445154,Sigma, USA, batch number: S30630); Colchicine (Xishuangbanna Pharmaceutical Co., Ltd., batch number: H53021369); Sodium urate (Shanghai Aladdin Biochemical Technology Co., Ltd., batch number: J2122579); Tween 80 (Tianjin Fuyu Fine Chemical Co., Ltd.); Sodium pentobarbital (Tianjin Damao Chemical Reagent Factory); 4% paraformaldehyde tissue fixative (Shanghai Biyuntian Biotechnology Co., Ltd.); Hematoxylin-eosin staining solution (Zhuhai Beso Biotechnology Co., Ltd.); Glacial acetic acid (Shanghai Pharmaceutical Group Chemical Reagent Co., Ltd.); Rat serum IL-1β detection kit (Nanjing Jiancheng Bioengineering Institute, batch number: 20201208); Rat serum IL-8 detection kit (Nanjing Jiancheng Bioengineering Institute, batch number: 20201113); Rat serum TNF-α detection kit (Nanjing Jiancheng Bioengineering Institute, batch number: 20211025);
Techniques: Control